Recent Computational/Bioinformatics Studies:

Stansfeld P.J. (2017) Computational studies of membrane proteins: from sequence to structure to simulation. Curr. Opin. Struct. Biol. 45:133-141

Domański J., Hedger G., Best R.B., Stansfeld P.J., Sansom M.S.P. (2017) Convergence and Sampling in Determining Free Energy Landscapes for Membrane Protein Association. J. Phys. Chem. B. 121:3364-3375.

Stansfeld P.J., Goose, J.E., Caffrey, M., Carpenter, E.P., Parker, J.L., Newstead, S., Sansom M.S.P. (2015) MemProtMD: Automated Insertion of Membrane Protein Structures into Explicit Lipid Membranes. Structure. 23:1350-1361.

Stansfeld P.J., Jefferys E.E., Sansom M.S.P. (2013). Multiscale simulations reveal conserved patterns of lipid interactions with aquaporins. Structure. 21:810-819.

Stansfeld P.J., Sansom M.S.P. (2011) From coarse grained to atomistic: a serial multiscale approach to membrane protein simulations. J. Chem. Theory Comput. 7: 1157–1166.

Stansfeld, P.J., Hopkinson, R., Ashcroft, F.M. & Sansom, M.S.P (2009). The PIP2 binding site in Kir channels: definition by multiscale biomolecular simulations. Biochem. 48:10926–10933.

Recent Collaborative Studies:

Gupta K, Donlan JA, Hopper JT, Uzdavinys P, Landreh M, Struwe WB, Drew D, Baldwin AJ, Stansfeld PJ, Robinson CV. (2017) The role of interfacial lipids in stabilizing membrane protein oligomers. Nature. 541:421-424.

Alcock F, Stansfeld PJ, Basit H, Habersetzer J, Baker MA, Palmer T, Wallace MI, Berks BC. (2016) Assembling the Tat protein translocase. Elife. e20718.

Gu Y, Li, H, Dong, H, Wang, Z, Zeng Y, Paterson NG, Stansfeld PJ, Wang, W, Dong, C. (2016) Structural basis of outer membrane protein insertion by the BAM complex. Nature 531:64-69

Vogeley, L, El Arnaout, T, Bailey, J, Stansfeld PJ, Boland, C, Caffrey, M. (2016) Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomycin. Science 351:876-880

Li, D, Stansfeld P.J., … Caffrey, M. (2015) Ternary structure reveals mechanism of a membrane diacylglycerol kinase. Nature Communications. 6:10140

Dong, H., Xiang, Q., Gu, Y., Wang, Z., Paterson, N.G., Stansfeld, P.J., He, C., Zhang, Y., Wang, W., & Dong, C. (2014) Structural basis for outer membrane lipopolysaccharide insertion. Nature 511: 52-56.

Rollauer, SE, Tarry, MJ, Graham, JE, Jaaskelainen, M, Jager, F, Johnson, S, Krehenbrink, M, Liu, SM, Lukey, MJ, Marcoux, J, McDowell, MA, Rodriguez, F, Roversi, P, Stansfeld, PJ, Robinson, CV, Sansom, MS, Palmer, T, Hogbom, M, Berks, BC, Lea, SM, Structure of the TatC core of the twin-arginine protein transport system. Nature, 2012. 492: 210.

Quigley, A, Dong, YY, Pike, AC, Dong, L, Shrestha, L, Berridge, G, Stansfeld, PJ, Sansom, MS, Edwards, AM, Bountra, C, von Delft, F, Bullock, AN, Burgess-Brown, NA, Carpenter, EP, The structural basis of ZMPSTE24-dependent laminopathies. Science, 2013. 339:1604.

Further Publications